You can reach out and book a demo and our team will be in touch with a personalized walkthrough based on your organization’s needs.

Metworx is designed for any organization involved in model-informed drug development (MIDD), data science, or quantitative research.

It can be used used across:

• Pharmaceutical and biotechnology companies – to scale pharmacometrics, PK/PD, and systems pharmacology modeling.

• Academic and research institutions – for teaching, collaborative modeling, and reproducible research.

• Regulatory agencies – to evaluate model-based submissions and support policy development.

• Healthcare and data science organizations – for simulation, analytics, and advanced computational workflows.

In short, Metworx supports any team that needs a secure, scalable, and collaborative cloud platform for scientific modeling and simulation.

Metworx has many attributes that will dovetail nicely with your organization’s quality assurance programs to establish suitability and fitness for use. 

Our software qualification suite, a scripted sequence of testing, is executed programmatically on each Metworx module build. This qualification testing suite provides documented evidence that the key computational software is installed correctly and operating as expected. 

The entire Metworx infrastructure is code based, version controlled, and highly managed. This makes it extraordinarily reproducible (cloneable, actually) and provides an audit trail of code base changes. 

Your Metworx system has built-in disaster recovery for both infrastructure and data. A rebuild of your Metworx system only takes a few minutes and data restoration from your most recent snapshot is fast and easy.

Your system runs within the Amazon Web Services (AWS) cloud ecosystem. AWS maintains strict physical and logical security controls in all of its operations and is audited by a highly regarded third party. The audit is performed against the SSAE 16 standard and documented through regularly published SOC reports.

Your individual data transmissions are encrypted while in transit using industry standard security protocols (SSL).

Because Metworx runs entirely in your AWS account, you maintain complete oversight and control of your Metworx resources. Your AWS account allows you to create and manage company and individual level security credentials. The AWS credentials entered by you are stored in the Metworx database so that they can subsequently be used to access and initiate Metworx resources within your AWS account.

To protect the security of these keys, they are automatically encrypted prior to being saved in the database. In addition, no records of the original unencrypted keys are kept and these values are explicitly excluded from any application log files that may be generated. The keys are dynamically unencrypted only as necessary to make calls to AWS services. Great care is taken to ensure the security of these keys, using the AWS best security practices as a guide. Optional 2-factor authentication is also available.

We provide full technical support for your Metworx environment, including initial configuration, user management, periodic software updates, and disaster recovery. We will provide training to your end-users with real-world workflows and computational examples and we will be available to respond to your support requests.

Once you are up and running, your workflow interactions will look just like they would on any system. Of course, you will really appreciate the availability and flexibility offered through the Metworx solution.

Although initially designed to handle big computation projects in biomedical modeling and simulation, any high-performance computing project can leverage the capabilities of Metworx.

Yes. Metworx is built to support both academic and regulatory use cases. Academic researchers use Metworx to enable reproducible, collaborative modeling and teaching in a secure, cloud-based environment.

Regulatory teams and sponsors use it to streamline model-informed drug development (MIDD) and ensure compliance with submission standards—supporting transparent, auditable workflows from model creation through review.

Metworx users have access to comprehensive support, onboarding, and a collaborative user community.

• Technical Support: Metrum Research Group provides full technical support for Metworx environments, including setup, user management, software updates, and troubleshooting. Support requests can be submitted directly through the platform or via the support team.

• Training & Onboarding: New users receive guided onboarding and hands-on training focused on real-world modeling and simulation workflows. Continued learning resources and documentation help teams adopt best practices in model-informed drug development (MIDD).

• Metworx User Group: Users are invited to join the Metworx User Group—a growing community of scientists, developers, and modelers who share insights, workflows, and feedback to shape the future of the platform.

• Ongoing Assistance: The Metworx team remains available for platform questions and optimization support, helping teams stay focused on science rather than infrastructure.

The Metworx Users Group (MUG) forum is for Metworx users to be able to connect, engage, share learnings, and ask questions in a supportive, friendly environment.