Principal Applied Data Science Engineer

Remote position located in the United States

The Principal Applied Data Science Engineer will play a vital role in providing technical expertise to Applied Data Science. As a subject matter expert, this role establishes best practices and standard frameworks for company-wide applied data science activities in an effort to support Metrum’s goal of defeating disease, especially in areas of unmet need.

You will help support the services and solutions of a global leading company in biomedical modeling & simulation with the mission of improving health and defeating disease. 


  • Work with scientists and other stakeholders to develop interactive scientific applications, primarily in the R shiny framework, to drive high-quality quantitatively-driven decisions.
  • Help define best practices and frameworks, and provide cross-team expertise on developing, deploying, and lifecycle maintenance of interactive scientific applications.
  • Actively participate in the development and maintenance of internal and open-source software to support scientific modeling and simulation work, including data processing, model diagnostics, and model traceability and reproducibility.
  • Assist in the building, deploying, and maintaining tools used in public cloud platforms such as AWS.
  • Potentially participate in advanced research as part of client-facing scientific services projects.

Qualifications (Required):

  • 5+ years of professional experience with scripting languages such as R or Python. 
  • Demonstrable expertise with the R programming language
  • Significant experience developing and deploying R packages and applications with emphasis on Shiny apps
  • Experience with RStudio Connect
  • Professional experience with version control systems such as git.
  • Experience in collaborating across teams, with scientists and less technical users, to build computationally efficient user-centric tools and software
  • A strong drive to learn and share learnings with others.

Ideal qualifications:

  • Significant experience with R internals, i.e. how R and RStudio interact with the system environment, dependency management in R, etc.
  • Significant experience developing and deploying R Shiny apps, ideally via RStudio Connect.
  • Applied data science and development experience using RStudio Workbench 
  • Experience supporting or doing scientific work, ideally in the life sciences.
  • Experience developing and releasing software packages/libraries/modules.
  • Experience with concurrency and parallel processing.

Education and Experience:

  • Bachelor's degree in Computer Science, Social Sciences, Physical Sciences, and Statistics required, or equivalent work experience
  • Masters/Ph.D. degree in Computer Science, Social Sciences, Physical Sciences, and Statistics preferred or equivalent work experience
  • Minimum 5+ year’s  of data science and/or programming experience
About Metrum Research Group

Metrum Research Group is a leading provider of biomedical modeling and simulation services in the U.S.A. and internationally. Founded in 2004, our experience spans R&D efforts for small molecule pharmaceuticals, biologic therapeutics, diagnostics, and medical device/drug-device combinations, across multiple therapeutic areas.

Metrum Research Group is an equal opportunity employer.